产品货号：
Z14981
中文名称：
Cyclin-T1/CCNT1抗体
英文名称：
Anti-Cyclin-T1/CCNT1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cyclin-T1/CCNT1 Antibody |
| 指标别名 | CCNT;CCNT1;Cyclin T;cyclin T1;CYCT1;HIVE1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC/IF,FCM |
| 基因名称 | CCNT1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Cyclin T1 (375-410aa QKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENM),different from the related mouse sequence by one amino acid. |
| 实际分子量 | 81KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene.This gene encodes a member of the highly conserved cyclin C subfamily.The encoded protein tightly associates with cyclin-dependent kinase 9,and is a major subunit of positive transcription elongation factor b (p-TEFb).In humans,there are multiple forms of positive transcription elongation factor b,which may include one of several different cyclins along with cyclin-dependent kinase 9.The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein,and is both necessary and sufficient for full activation of viral transcription.This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit.Overexpression of this gene is implicated in tumor growth.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | O60563 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cyclin T1 |
| 蛋白名全称 | Cyclin-T1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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